Modifier 24 and Modifier 79

Controlling Accessibility in Agile Projects with the Access Modifier Modifier

Access modifiers like public and private let the programmer control the accessibility of class members. Restricted accessibility supports encapsulation, i.e., the hiding of implementation details behind the interface of a class. However, what is an implementation detail and what makes the interface of a class is often subject to change: especially in an agile setting (with absence of an upfront...

Modeling covalent-modifier drugs.

In this review, we present a summary of how computer modeling has been used in the development of covalent-modifier drugs. Covalent-modifier drugs bind by forming a chemical bond with their target. This covalent binding can improve the selectivity of the drug for a target with complementary reactivity and result in increased binding affinities due to the strength of the covalent bond formed. In...

Modifier genes and oligogenic disease.

It is now increasingly apparent that modifier genes have a considerable role to play in phenotypic variations of single-gene disorders. Intrafamilial variations, altered penetrance, and altered severity are now common features of single gene disorders because of the involvement of several genes in the expression of the disease phenotype. Oligogenic disorders occur because of a second gene modif...

Modifier Graph Based Subtopic Mining

Given a role-explicit topic, we firstly determine its kernel-object, then we construct the corresponding modifier graph (Step-1). We perform graph clustering on the induced modifier graph using the algorithm by Noack [4]. Each modifier cluster is viewed as a representation of a particular subtopic. Corresponding to each modifier cluster, we generate the clusters of subtopic strings based on the...

Corpus-based NP Modifier Generation